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Reference Documents

date: 2018-01-28 14:33:48 click:

Drug Transporter Based DDI

1st

Takao Watanabe, Hiroyuki Kusuhara, Tomoko Watanabe, Yasuyuki Debori, Kazuya Maeda, Tsunenori Kondo, Hideki Nakayama, Shigeru Horita, Brian W. Ogilvie, Andrew Parkinson, Zhuohan Hu and Yuichi Sugiyama 

 

 

Prediction of the overall renal tubular secretion and hepatic clearance of anionic drugs and a renal drug-drug interaction involving OAT3 in humans by in vitro uptake experiments. Drug MetabDispos.2011,39: 1031-1038. 

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2nd 

Watanabe,T., Kusuhara,H., Maeda,K., Kanamaru,H., Saito,Y., Hu,Z. and Sugiyama,Y. 

 

 

Investigation of the rate-determining process in the hepatic elimination of HMG-CoA reductase inhibitors in rats and humans. Drug MetabDispos2010, 38, 215-222 

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3rd

Wakaba Yamashiro, Kazuya Maeda, Masakazu Hirouchi, Yasuhisa Adachi, Zhuohan Hu,and Yuichi Sugiyama 

Involvement of transporters in the hepatic uptake and biliary excretion of valsartan, a selective antagonist II AT-receptor, in humans.  Drug MetabDispos2006, 37, 1247 - 1254

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4th 

Yoshimichi Sai1, Yukio Kato1, Keiko Nakamura1Sayaka Kato1, Tomohiro Nishimura1, Yoshiyuki Kubo1Ikumi Tamai2, Shu Yang3Zhuohan Hu3Ichimaro Yamada4 and Akira Tsuji. 

 

Carrier-mediated hepatic uptake of a novel non-renal excretion type uric acid generation inhibitor, Y-700. Journal of Pharmacology Science .2006, (95): 236

 

Drug Metabolism Based DDI

 

5th 

Bent H. HellumZhuohan Hu, Odd Georg Nilsen

 

 

The Induction of CYP1A2, CYP2D6 and CYP3A4 by Six Trade Herbal Products in Cultured Primary Human Hepatocytes. Basic & Clinical Pharmacology & Toxicology. 2007, 100: 23-30

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